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Standard Colon Cancer Linked to microRNA Gene

Clinical Outcomes in Colon Cancer Linked to microRNA Gene

Colon tumors that produced high expression levels of a microRNA gene called miR-21 were associated with poor survival and therapeutic outcome in two patient populations, one in the U.S. and the other in China, according to a study in the January 30 Journal of the American Medical Association

Like other microRNA genes, produces short strands of RNA that control multiple genes, including some involved in cancer. The findings support a growing view that this gene, which shows increased activity in more than a dozen major cancers, may be a useful biological marker and therapeutic target.

Quelle: http://www.cancer.gov/ncicancerbulletin/NCI_Cancer_Bulletin_020508/page3#b

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